Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2073AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOINo cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2074AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining1 MOISome cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2075AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining10 MOIAll cells was deadNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2076AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining100 MOIAll cells was deadNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2089AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2090AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2091AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2092AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2093AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANANANANABALB/c nude mice xenograft for SW620 cell line (5.0E+6 cells)2.0E+9 pfuNA Reduction in tumor volume below 100 mm after 9 weeksNAInduction of apoptosisNANA21794078
OV_2102AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2103AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining1 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2104AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining10 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2105AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining100 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2122AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2123AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining1 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2124AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining10 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2125AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining100 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_3048Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI100% cell viabilityNoNoNA No responseNANANANA31011628
OV_3049Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI70% cell viabilityNoNoNA No responseNANANANA31011628
OV_3050Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻² MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3072Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3073Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻³ MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3074Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3078Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI100% cell viabilityNoNoNA No responseNANANANA31011628
OV_3079Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI70% cell viabilityNoNoNA No responseNANANANA31011628
OV_3080Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻² MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3102Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3103Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3104Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell deathNoNoNA No responseNANANANA31011628
OV_3105Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500mm after 50 daysIntravenousNANANA31011628
OV_3106Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 500mm after 50 daysIntravenousNANANA31011628
OV_3107Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3108Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 250 mm after 50 daysIntravenousNANANA31011628
OV_3117Vaccinia virusVaccinia virus deltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500 mm after 50 daysIntravenousNANANA31011628
OV_3118Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3141Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3142Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI25% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3143Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI18% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3144Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay5 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3145Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI30% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3146Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay20 MOI25% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3147Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI90% cell viability after day 1NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3148Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI60% cell viability after day 2NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3149Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI40% cell viability after day 3NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3150Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI10% cell viability after day 4NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3151Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI90% cell viability after day 1NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3152Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI80% cell viability after day 2NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3153Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI70% cell viability after day 3NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3154Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI40% cell viability after day 4NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3155Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW620NANANANANAMouse model xenograft for SW620 (1.0E+6)5.0E+8 pfuNA Reduction in tumor volume below 200mm as compared to control 2500mm after 24 daysIntratumoralCaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3156Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174TNANANANANAMouse model xenograft for LS174T (1.0E+6)5.0E+8 pfuNA Reduction in tumor volume below 500mm as compared to control 3000mm after 24 daysIntratumoralCaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3157Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (5nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI60% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3158Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (10nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3159Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (20nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI40% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3160Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (5nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay5 MOI70% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3161Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (10nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay10 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3162Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (20nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineLS174T2000 cells per wellNACCK-8 assay20 MOI40% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3298Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 81.1% as compared to control 100% after day 3IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3299Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 89.7% as compared to control 100% after day 5IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3300Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 80.7% as compared to control 100% after day 8IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3301Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 71.9% as compared to control 100% after day 10IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3302Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 68.1% as compared to control 100% after day 12IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3303Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 58.4% as compared to control 100% after day 15IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3304Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 57.1% as compared to control 100% after day 17IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3305Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 58.3% as compared to control 100% after day 19IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3306Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 67.8% as compared to control 100% after day 3IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3307Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 60.8% as compared to control 100% after day 5IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3308Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 62.4% as compared to control 100% after day 8IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3309Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 64.7% as compared to control 100% after day 10IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3310Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 64.4% as compared to control 100% after day 12IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3311Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 61.5% as compared to control 100% after day 15IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3312Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 59.7% as compared to control 100% after day 17IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3313Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 59.9% as compared to control 100% after day 19IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3673Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3674Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOI10% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3675Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3676Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI70% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3689Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3690Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOI75% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3691Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3692Mumps viruswild typeRNAParamyxoviridaeNoneYesNoNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI75% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3705Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOI70% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3706Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman colon cancer cell lineHT-295000 cells per wellNAMTT assay1 MOIComplete cell death after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3707Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI80% cell viability after day 3NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3708Measles and mumps viruswild typeRNAParamyxoviridaeNoneNoMeasles virus in combination with mumps virusNoATCCHuman colon cancer cell lineHCT-1165000 cells per wellNAMTT assay1 MOI50% cell viability after day 6NoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29485292
OV_3775Newcastle disease virusNDVstrain 852RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU30% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3776Newcastle disease virusNDVstrain 770RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU38% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3777Newcastle disease virusNDVstrain 320RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU44% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3778Newcastle disease virusNDVstrain 373RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU55% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3779Newcastle disease virusNDVstrain 321RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU58% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3780Newcastle disease virusNDVstrain 264RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU58% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3781Newcastle disease virusNDVstrain 776RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU62% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3782Newcastle disease virusNDVstrain 880RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU65% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3783Newcastle disease virusNDVstrain 14RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU70% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3784Newcastle disease virusNDVstrain 329RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU70% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3785Newcastle disease virusNDVstrain 485RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU80% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3786Newcastle disease virusNDVstrain 718RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU82% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3787Newcastle disease virusNDVstrain 53RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU85% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3788Newcastle disease virusNDVstrain 52RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU85% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3789Newcastle disease virusNDVstrain 746RNAParamyxoviridaeNoneYesNoNoState centre for virology and biotechnology, RussiaHuman colon carcinoma cell lineHCT-11610000 cells per wellNAMTT assay16 HAU85% cells viability after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357